Study of 211Bi and 211Pb recoils release from 223Ra labelled TiO2 nanoparticles just published!

Nanoparticles of various materials were proposed as carriers of nuclides in targeted alpha particle therapy to at least partially eliminate the nuclear recoil effect causing the unwanted release of radioactive progeny originating in nuclear decay series of so-called in vivo generators. Here, we report on the study of 211Pb and…

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New paper on the nanotechnology in radiopharmacy just appeared!

Check our newest review paper in EJNMMI Radiopharmacy and Chemistry on the topic “Radiolabeled nanomaterials for biomedical applications: radiopharmacy in the era of nanotechnology”. Sahylí Ortega Pijeira, M.; Viltres, H.; Kozempel, J.; Sakmár, M.; Vlk, M.; İlem‑Özdemir, D.; Ekinci, M.; Srinivasan, S. et al.: Radiolabeled nanomaterials for biomedical applications: radiopharmacy…

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Next article on Radium sorption available!

New article entitled “Study of ²²³Ra uptake mechanism on hydroxyapatite and titanium dioxide nanoparticles as a function of pH” have been just published in RSC Advances. It develops futher our studies of nanomaterials suitable for Radium sorption. The article fulltext could be downloaded free of charge at DOI:10.1039/C9RA08953E.  

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New article in RSC Advances!

New article entitled “Surface protolytic property characterization of hydroxyapatite and titanium dioxide nanoparticles” have been just published in RSC Advances. It deals with surface protolytic property characterization of hydroxyapatite and titanium dioxide nanoparticles that are important materials for many applications. The article fulltext as well as electronic supplementary information could…

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New paper on “In Situ In Vivo radiolabeling of polymer-coated hydroxyapatite nanoparticles to track their biodistribution in mice” is out!

Our new paper entitled “In Situ In Vivo radiolabeling of polymer-coated hydroxyapatite nanoparticles to track their biodistribution in mice just appeared in Colloids and surfaces B: Biointerfaces  (DOI: 10.1016/j.colsurfb.2019.03.057). The imaging of healthy tissues and solid tumors benefits from the application of nanoparticle probes with altered pharmacokinetics, not available to…

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New review article “Progress in Targeted Alpha-Particle Therapy. What We Learned about Recoils Release from In Vivo Generators” published in Molecules journal.

New review article: “Progress in Targeted Alpha-Particle Therapy. What We Learned about Recoils Release from In Vivo Generators” was published in the Molecules journal. This review summarizes recent progress and developments as well as the most important pitfalls in targeted alpha-particle therapy, covering single alpha-particle emitters as well as in…

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Papers trilogy on quantitative biokinetics of titanium dioxide nanoparticles just published online!

The biokinetics and clearance of a low single dose (typically 40-400 µg/kg BW) of 48V-radiolabeled, pure TiO2 anatase nanoparticles ([48V]TiO2NP) with a median aggregate/agglomerate size of 70 nm in aqueous suspension after intravenous injection into female Wistar rats. Biokinetics and clearance were followed from 1-hour to 4-weeks. The use of radiolabeled…

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