Nanoparticles of various materials were proposed as carriers of nuclides in targeted alpha particle therapy to at least partially eliminate the nuclear recoil effect causing the unwanted release of radioactive progeny originating in nuclear decay series of so-called in vivo generators. Here, we report on the study of 211Pb and…
Check our newest review paper in EJNMMI Radiopharmacy and Chemistry on the topic “Radiolabeled nanomaterials for biomedical applications: radiopharmacy in the era of nanotechnology”. Sahylí Ortega Pijeira, M.; Viltres, H.; Kozempel, J.; Sakmár, M.; Vlk, M.; İlem‑Özdemir, D.; Ekinci, M.; Srinivasan, S. et al.: Radiolabeled nanomaterials for biomedical applications: radiopharmacy…
New article entitled “Study of ²²³Ra uptake mechanism on hydroxyapatite and titanium dioxide nanoparticles as a function of pH” have been just published in RSC Advances. It develops futher our studies of nanomaterials suitable for Radium sorption. The article fulltext could be downloaded free of charge at DOI:10.1039/C9RA08953E.
New article entitled “Surface protolytic property characterization of hydroxyapatite and titanium dioxide nanoparticles” have been just published in RSC Advances. It deals with surface protolytic property characterization of hydroxyapatite and titanium dioxide nanoparticles that are important materials for many applications. The article fulltext as well as electronic supplementary information could…
Our new paper entitled “In Situ In Vivo radiolabeling of polymer-coated hydroxyapatite nanoparticles to track their biodistribution in mice just appeared in Colloids and surfaces B: Biointerfaces (DOI: 10.1016/j.colsurfb.2019.03.057). The imaging of healthy tissues and solid tumors benefits from the application of nanoparticle probes with altered pharmacokinetics, not available to…
Come to see us at 11th TAT symposium in Ottawa, Canada – great opportunity to see the latest results of the worldwide research efforts in the field of targeted alpha-particle therapy! More info at: www.tat11.com
The participation of our Ph.D. student Ms. Petra Suchánková (Mičolová) in the Becquerel prize award competition resulted in excellent 2nd place. The prize is awarded by the Electricité de France and ATMEA companies together with the Embassy of the France in the Czech Republic. The prize was awarded to P. Suchánková for her…
New review article: “Progress in Targeted Alpha-Particle Therapy. What We Learned about Recoils Release from In Vivo Generators” was published in the Molecules journal. This review summarizes recent progress and developments as well as the most important pitfalls in targeted alpha-particle therapy, covering single alpha-particle emitters as well as in…
The biokinetics and clearance of a low single dose (typically 40-400 µg/kg BW) of 48V-radiolabeled, pure TiO2 anatase nanoparticles ([48V]TiO2NP) with a median aggregate/agglomerate size of 70 nm in aqueous suspension after intravenous injection into female Wistar rats. Biokinetics and clearance were followed from 1-hour to 4-weeks. The use of radiolabeled…
